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汪洋(副教授)

所属单位:湖北工业大学生物工程与食品学院

担任职务:副教授

擅长领域:

联系方式:027-59750483 邮箱:登录后查看

汪洋,副教授,博士,硕士生导师,湖北省相关人才项目入选者,“3551光谷人才计划”入选者。研究方向为溶瘤病毒(OH2)抗肿瘤机制研究;I类抗肿瘤新药OH2的临床前研究和临床试验;病毒激活免疫细胞(VAK)抗肿瘤分子机制研究与临床研究。主持国家自然科学基金青年基金1项,企业横向课题4项。参与国家重大新药创制科技重大专项、国家自然科学基金面上项目、Bill&Melinda Gates Foundation等项目。获黑龙江省科技进步三等奖一项,在Human Gene therapy, BMC Genomics,Developmental and Comparative Immunology, Scientific Reports等SCI杂志上第一作者或共同第一作者发表论文10篇。 工作、学习经历: 2018.08-至今 湖北工业大学 副教授 2015.08-2018.07 湖北工业大学 讲师 2014.10-2015.03 非盟-泛非洲动物疫苗中心(AU-PANVAC)访问交流 2012.07-2015.07 中国农业科学院哈尔滨兽医研究所 兽医生物技术国家重点实验室 助理研究员 2007.09-2012.06 华中农业大学动物医学院 农业微生物学国家重点实验室 (硕博连读)博士 2003.09-2007.08 长江大学生命科学学院 学士

主要成就

代表性论文: 1) Preclinical safety evaluation of oncolytic herpes simplex virus type 2. Yang Wang, Xiaobing Zhou, Zhen Wu, Han Hu, Jing Jin, Yanping Hu, Yuting Dong, Jianwen Zou, Zeyong Mao, Xiaotai Shi, Yan Huo, Jianjun Lyu, Zhizheng Fang, Wen Zhang, Yujie Zhu, Bo Li, Binlei Liu. Human Gene therapy, 2019, 30:651-660. 2) Stability and anti-tumor effect of oncolytic herpes simplex virus type 2. Yang Wang, Jing Jin, Zhen Wu, Sheng Hu, Han Hu, Zhifeng Ning, Yanfei Li, Yuting Dong, JianwenZou, Zeyong Mao, Xiaotai Shi, Huajun Zheng, Shuang Dong, Fuxing Liu, Zhizheng Fang, Jiliang Wu and Binlei Liu. Oncotarget, 2018, 9:24672-24683. 3) Transcription analysis on response of porcine alveolar macrophages to Haemophilus parasuis. Yang Wang, Chong Liu, Ying Fang, Xiaoli Liu, Wentao Li, Shuqing Liu, Yingyu Liu, Yuxi Liu, Catherine Charreyre, Jean Christophe Audonnet, Pin Chen, Qigai He. BMC Genomics, 2012, 13:68. 4) Mycoplasma bovis-derived lipid-associated membrane proteins activate IL-1β production through the NF-κB pathway via Toll-like receptor 2 and MyD88. Yang Wang, Suli Liu, Yuan Li, Qi Wang, Jiari Shao, Ying Chen, Jiuqing Xin, Developmental and Comparative Immunology 2016, 55: 111-118 5) Porcine Coronin 1A contributes to inhibit NF-κB activation during Haemophilus parasuis infection. Chong Liu#, Yang Wang #, Hengling Zhang, Shuang Cheng, Xiaoli Liu, Xiaofei Wang, Catherine Charreyre, Jean Christophe Audonnet, Pin Chen, Rui Zhou, Huanchun Chen, Qigai He*.Plos One 2014, 8:e103904 6)Mmm-derived lipid-associated membrane proteins activate IL-1b production through the NF-κB pathway via TLR2, MyD88, and IRAK4. Yang Wang, Qi Wang, Yuan Li, Ying Chen, Jiari Shao, Nick Nwankpa, Chunyan Li, Jiuqing Xin. Scientific Reports, 2017,7:4349. 7)Changes in pathogenicity and immunogenicity of Mycoplasma mycoides subsp. mycoides strains revealed by comparative. Yuan Li#, Yang Wang #, Wang Rui, Yongqiang Zhu, Suli Liu, Qi Wang, Jiari Shao, Ying Chen, Liping Gao, Changping Zhou, Henggui Liu1, Xiumei Wang, Huajun Zheng and Jiuqing Xin. Scientific Reports, 2016,6:19081. 8)P19 contribute to Mycoplasma mycoides subsp. mycoides adhesion to EBL cells. Yumei Zhou #, Yang Wang#, Yuan Li , Nwankpa Nick , Xiaohui Zou 1,Fan Bai , Jindi Wu , Jiuqing Xin. Microbial Pathogenesis. 2016, 93:13-21 9) Loop-mediated isothermal amplification targeting the apxIVA gene for detection of Actinobacillus pleuropneumoniae. Yang Wang, Pin Chen, Haibing Guo, Yang Chen, Hui Liu, Qigai He. FEMS Microbiology Letters, 2009, 300: 83-89 10) Development and evaluation of loop-mediated isothermal amplification for rapid detection of Haemophilus parasuis. Yang Wang, Ying Fang, Yingyu Liu, Pin Chen, Wentao Li, Shuqing Liu, Haoyong Zou, Qigai He. FEMS Microbiology Letters, 2010, 313:54-60. 11) Molecular cloning and characterization of a new variable surface protein in a Mycoplasma bovis Hubei-1 Strain. Xiaohui Zou, Yuan Li, Yang Wang, Yumei Zhou, Yang Liu, Jiuqing Xin*. Plos One, 2013, 8:69644 12) Proteomic analysis of porcine alveolar macrophages infected with porcine circovirus type 2. Shuang Cheng, Min Zhang, Wentao Li, Yang Wang, Yingyu Liu, Qigai He. Journal of Proteomics, 2012, 75:3258-3269 13) Transcription analysis of the porcine alveolar macrophage response to porcine cirovirus type 2, Wentao Li, Shuqing Liu, Yang Wang, Feng Deng, Weidong Yan, Kun Yang, Huanchun Chen, Qigai He, Catherine Charreyre, Jean-Christophe Audoneet. BMC Genomics,2013 14:353 14) Transcriptional Profiling of Haemophilus parasuis SH0165 Response to Tilmicosin. Yingyu Liu, Pin Chen, Yang Wang, Wentao Li, Shuang Cheng, Chunmei Wang, Anding Zhang, and Qigai He. Microbial Drug Resistance, 2012, 18 (6):604-15 15) Porcine reproductive and respiratory syndrome virus nonstructural protein 2 contributes to NF-κB activation. Ying Fang, Liurong Fang, Yang Wang, Yingying Lei, Rui Luo, Dang Wang, Huanchun Chen and Shaobo Xiao. Virology Journal, 2012, 9:83. 16) Broad activity against porcine bacterial pathogens displayed by two insect antimicrobial peptides moricin and cecropin B. Han Hu, Chunmei Wang, Xiaozhen Guo,Wentao Li, Yang Wang, Qigai He. Molecules and Cells, 2013, 35:106-114. 17) Efficacy of single dose of an inactivated porcine circovirus type 2 (PCV2) whole-virus vaccine with oil adjuvant in piglets. Kun Yang, Wentao Li, Huihui Niu, Weidong Yan, Xiaoli Liu, Yang Wang, Shuang Cheng, Xugang ku and Qigai He. Acta Veterinaria Scandinavica, 2012, 54,67. 18) Treatment of colon cancer with oncolytic herpes simplex virus in preclinical models. H Yang, T Peng, J Li, Yang W, W Zhang, P Zhang, S Peng, T Du, Y Li, Q Yan and B Liu. Gene Therapy, 2016,23: 450-459 19) BGC823 Cell Line with the Stable Expression of iRFP720 Retains Its Primary Properties with Promising Fluorescence Imaging Ability. Han H, Ziyi Z, Runyang W, Yang W, Jing J, Linkang C, Junhan Yang, Haixiao D, Zhen W, Zhizheng F and Binlei L. Dna and Cell Biology, 2020, DOI:10.1089/dna.2019.5057