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创新资源平台
服务平台首页>协同创新>专家库>专家详情

孔岩(教授)

所属单位:东南大学医学院

担任职务:

擅长领域:

联系方式:025-83272500 邮箱:登录后查看

研究方向

神经系统疾病的基因表达调控机制研究

荣誉奖励

江苏省生物化学与分子生物学实验教学暨青年教师授课竞赛二等奖

主要成就

Zhou W, He Y, Rehman AU, Kong Y, et al. Loss of function of NCOR1 and NCOR2 impairs memory through a novel GABAergic hypothalamus-CA3 projection. Nat Neurosci. 2019 Feb;22(2):205-217.Kong Y, Jiang B, Luo X. Gut microbiota influences Alzheimer's disease pathogenesis by regulating acetate in Drosophila model. Future Microbiol. 2018 Aug;13:1117-1128. Kong Y, Li K, Wan C, et al. Quercetin ameliorates Aβ toxicity in Drosophila AD model by modulating cell cycle-relatedprotein expression. Oncotarget. 2016 Oct 18;7(42):67716-67731.Kong Y, Liang X, Liu L, et al. High Throughput Sequencing Identifies MicroRNAs Mediating α-Synuclein Toxicity by Targeting Neuroactive-Ligand Receptor Interaction Pathway in Early Stage of Drosophila Parkinson's Disease Model. PLoS One. 2015 Sep 11;10(9):e0137432.Kong Y, Wu J, Yuan L. MicroRNA expressionanalysis of adult-onset Drosophila Alzheimer's disease model. Curr Alzheimer Res. 2014;11(9):882-91Kong Y, Wu J, Zhang D, et al. The Role of miR-124 in Drosophila Alzheimer’s Disease Model by Targeting Delta in Notch Signaling Pathway. Curr Mol Med. 2015; 15(10):980-9Kong Y, Ruan L, Qian L,Liu X, Le Y. Norepinephrine promotes microglia to uptake and degrade amyloid beta peptide through upregulation of mouse formyl peptide receptor 2 and induction of insulin-degrading enzyme. J Neurosci. 2010 Sep 1;30(35):11848-57.Kong Y, Ruan L, Ma L,Cui Y, Wang JM, Le Y. RNA interference as a novel and powerful tool in immunopharmacological research. Int Immunopharmacol. 2007 Apr;7(4):417-26.Kong Y, Le Y. Toll-likereceptors in inflammation of the central nervous system. Int Immunopharmacol. 2011May 18. Oct;11(10):1407-14.Li K, Kong Y, ZhangM, Xie F, Liu P, Xu S. Differentiation of pluripotent stem cells for regenerative medicine. Biochem Biophys Res Commun. 2016 Feb26;471(1):1-4.