最后学位:哲学博士(Ph.D.,北京大学) 职称职务:教授、博导 专业方向:肿瘤生物学 研究方向:DNA损伤修复的分子机制;表观遗传调控肿瘤发生 电话号码:027-68750036 电子邮件:c52616@hotmail.com |
教育经历
1998-2002 山东大学生命科学学院, 学士
2002-2008 北京大学生命科学学院, 博士
工作经历与任职
2008-2010 北京大学生命科学学院, 博士后
2010-2015 美国密西根大学医学院, 博士后
2015-2016 美国希望之城贝克曼研究所,博士后
2016-至今 武汉大学医学研究院, 教授
代表性论文
1.Chen, Q. and Yu, X. (2016) OGT restrains the expansion of DNA damage signaling. Nucleic acids research.
2.Zhuo, X., Guo, X., Zhang, X., Jing, G., Wang, Y., Chen, Q., Jiang, Q., Liu, J. and Zhang, C. (2015) Usp16 regulates kinetochore localization of Plk1 to promote proper chromosome alignment in mitosis. The Journal of cell biology, 210, 727-735.
3. Bian, C., Chen, Q. and Yu, X. (2015) The zinc finger proteins ZNF644 and WIZ regulate the G9a/GLP complex for gene repression. eLife, 4.
4.Wang, G., Chen, Q., Zhang, X., Zhang, B., Zhuo, X., Liu, J., Jiang, Q. and Zhang, C. (2013) PCM1 recruits Plk1 to the pericentriolar matrix to promote primary cilia disassembly before mitotic entry. Journal of cell science, 126, 1355-1365.
5. Chen, Q., Chen, Y., Bian, C., Fujiki, R. and Yu, X. (2013) TET2 promotes histone O-GlcNAcylation during gene transcription. Nature, 493, 561-564.
6.Zhang, X., Chen, Q., Feng, J., Hou, J., Yang, F., Liu, J., Jiang, Q. and Zhang, C. (2009) Sequential phosphorylation of Nedd1 by Cdk1 and Plk1 is required for targeting of the gammaTuRC to the centrosome. Journal of cell science, 122, 2240-2251.
7. Chen, Q., Zhang, X., Jiang, Q., Clarke, P.R. and Zhang, C. (2008) Cyclin B1 is localized to unattached kinetochores and contributes to efficient microtubule attachment and proper chromosome alignment during mitosis. Cell research, 18, 268-280.