学习经历 2000–2007，中国科学院微生物研究所，博士 1996–2000，浙江大学农业与生物技术学院，学士 工作经历 2019-， 农业微生物与生物技术研究室，副主任 2017–， 中科院微生物所，课题组长 2014–2017，中科院微生物所，青年课题组长 2013–2014，新加坡国立大学淡马锡生命科学研究院，Principal Investigator 2011–2013，新加坡国立大学淡马锡生命科学研究院，Biotechnology Manager 2009–2010，新加坡国立大学淡马锡生命科学研究院，Research Fellow 2007–2009，新加坡国立大学淡马锡生命科学研究院，博士后 获奖 浙江大学 竺可桢奖学金 研究方向 1. 虫媒病毒—植物—介体昆虫互作的分子机理；2. 植物油脂代谢产物在抗病免疫中的作用 研究内容及意义 1. 全球气候变暖，极端天气频发，入侵型、新发和重发昆虫传作物病毒病害已经成为限制我国农作物优质高产的主要因素。因缺乏抗病抗虫的种质资源、育种周期长，虫传病害防治难度极大，目前处于几乎完全依赖化学防控媒介昆虫的被动应付局面，生态与环境成本极大。以往研究虫传病毒病害往往注重病毒和植物寄主两个方面，这些研究为理解作物病毒病害的爆发机制提供了基础知识，但对于病害防控的关键节点—媒介昆虫介导的病毒侵染循环这一根本性问题上尚较缺乏，导致目前在病毒病害防治实践上缺乏有效抓手。近年来，随着分子生物学和组学研究的飞速发展，本课题组致力于将微观生物学技术和理念，整合宏观生物学的现象和规律，寻找病毒病害流行爆发的宏观生态学现象背后的分子生物学与生物化学机制，努力建立复杂生态系统多元互作分子机制提供数学模型，并利用自然规律设计人工干扰和操纵生物间互作关键节点，变被动应付为主动调控病害灾变过程。具体研究成果参见近期代表工作1和近期代表工作2。 2. 植物脂肪酸和油脂代谢相关遗传因子在植物免疫识别和信号传导过程中发挥了重要作用，我们的研究将着重于植物免疫相关代谢物的发掘和功能鉴定，并应用于作物的分子品种设计，培育优质、高产新品种。

著书章节（*通讯作者, #共同第一作者) Ma YH, Ye J*. 2017. Lipid biosynthesis and regulation in Jatropha curcas, an emerging model for woody energy plants. The Jatropha Genome. Compendium of Plant Genomes. Suguru Tsuchimoto (Ed.) Jatropha. Springer Science Publishers, New York. Ye J, Wang CM, Yue GH. 2017. Jatropha breeding. The Jatropha Genome. Compendium of Plant Genomes. Suguru Tsuchimoto (Ed.) Jatropha. Springer Science Publishers, New York. Ye J*, Hong Y, Qu J, Wang CM. 2012. Improvement of Jatropha oil by genetic transformation. Jatropha, Challenges for a New Energy Crop-Genetic Improvement and Biotechnology, vol. 2. Springer Science Publishers, New York. Qu J, Ye J, Fang RX. 2012. Artificial MicroRNAs for Plant Virus Resistance, Antiviral Resistance in Plants: Methods and Protocols, Methods in Molecular Biology, vol. 894 发表论文（*通讯作者, #共同第一作者) 2019年 Zhao PZ, Yao XM, Cai CX, Li R, Du J, Sun YW, Wang MY, Zou Z, Wang QM, Kliebenstein DJ , Liu SS, Fang RX and Ye J*. Viruses mobilize plant immunity to deter non-vector insect herbivores. Science Advances. DOI: 10.1126/sciadv.aav9801. Wu XJ#, Xu S#, Zhao PZ, Zhang X, Yao XM, Sun YW，Fang RX, Ye J*. The Orthotospovirus nonstructural protein NSs suppresses plant MYC-regulated jasmonate signaling leading to enhanced vector attraction and performance. PLoS Pathogens. DOI:10.1371/journal.ppat.1007897. Wang N, Zhao PZ, Ma YH, Yao XM, Sun YW, Huang XD, Jin JJ, Zhang YJ, Zhu CX, Fang RX, Ye J*, A whitefly effector Bsp9 targets host immunity regulator WRKY33 to promote performance. Philos. Trans. Roy. Soc. B, 2019. 374: 20180313. 2018年 Wang D, Yao, XM, Huang GX, Shi T, Wang GF, Ye J*, First report of Sri Lankan cassava mosaic virus infected cassava in China, Plant Disease 2018, DOI: 10.1094/PDIS-09-18-1590-PDN Ye J*， Wang CM， Sun YW， Qu J， Mao HZ， Chua NH*. 2018. Overexpression of JcWRI1 in Jatropha elevated seed lipid content and increased seed mass. Frontiers in Plant Sciences, 2018. fpls.2018.01479 2017年 叶 健*，龚雨晴，方荣祥*，病毒—媒介昆虫—植物三者互作研究进展及展望. 中国科学院院刊.已接收 Sun YW#, Wang CM#, Wang N#, Jiang XY, Mao HZ, Zhu CX, Wen FJ, Wang XH, Lu ZJ, Yue GH, Xu ZF, Ye J*. 2017. Manipulation of Auxin Response Factor 19 affects seed size in the woody perennial Jatropha curcas. Scientific reports. 7: 40844. Jin JJ, Sun YW#, Qu J, Rahmadsyah, Lim CH, Alfiko Y, NurEstyaBte Rahman, Suwanto A, Yue GH, Wong LS, Chua NH, Ye J*. 2017. Transcriptome and functional analysis reveals hybrid vigor for oil biosynthesis in oil palm. Scientific reports. 7: 439. 2016年 Jun Liu#, Shulin Deng#, HW Wu#, Ye J, Hui-Wen Wu, Hai-Xi Sun, and Nam-Hai Chua. 2016. CURLY LEAF Regulates Gene Sets Coordinating Seed Size and Lipid Biosynthesis in Arabidopsis. Plant physiology. 17 (1) 424-436. Tang W#, Wu T#, Ye J, Sun J, Jiang Y, Yu J, Tang J, Chen G, Wang C, Wan J. 2016. SNP-based analysis of genetic diversity reveals important alleles associated with seed size in rice. BMC Plant Biology 16:93. Wang N#, Yao YM#, Zhu CX, Wen FJ*, Ye J*. 2016 Towards sustainable protection against insect-borne plant viral diseases: phytohormones and beyond. Science Foundation in China. 24(2). Review. Cover Pingzhi Zhao, Lubomir N. Sokolov, Ye Jian, Cheng-Yi Tang, Jisen Shi, Yan Zhen, Wenzhi Lan, Zhi Hong, Jinliang Qi, Gui-Hua Lu, Girdhar K. Pandey & Yong-Hua Yang. 2016 The LIKE SEX FOUR2 regulates root development by modulating reactive oxygen species homeostasis in Arabidopsis. Scientific reports. srep28683. Jin JJ#, Lee M#, Bai B#, Sun Yanwei#, Qu J, Rahmadsyah, Yuzer A, Lim CH, Suwanto A, Sugiharti M, Wong LS, Ye Jian*, Chua NH* and Yue GH*. 2016 Draft genome sequence of an elite Dura palm and whole-genome patterns of DNA variation in oil palm. DNA Research. 23:527. 龚雨晴，姚香梅，徐爽，孙艳伟，王宁，马永焕，赵平芝，应晓宝，叶健*. 微生物组学研究与经济作物虫传病害的绿色防控. 《植物保护与农产品安全》 2016年12月 2015年 Ye J*, Yang J, Sun Y, Zhao P, Gao S, Jung C, Qu J, Fang R, Chua NH*. 2015. Geminivirus Activates ASYMMETRIC LEAVES 2 to Accelerate Cytoplasmic DCP2-Mediated mRNA Turnover and Weakens RNA Silencing in Arabidopsis. PLoS pathogens 11:e1005196. Sun YW#, Tee CS#, Ma YH#, Wang G, Yao XM, Ye J*. 2015. Attenuation of Histone Methyltransferase KRYPTONITE-mediated transcriptional gene silencing by Geminivirus. Scientific reports 5:16476. Li R, Tee C, Jiang Y, Jiang X, Venkatesh P, Sarojam R, Ye J*. 2015. A terpenoid phytoalexin plays a role in basal defense of Nicotiana benthamiana against Potato virus X. Scientific reports 5:9682. Wang H NQ, Wu HW, Liu J, Ye J, Yu N, Chua NH. 2015. Analysis of noncoding transcriptome in rice and maize uncovers roles of conserved lncRNAs associated with agriculture traits. The Plant Journal 84 2: 404-416. Lee M, Xia J, Zou Z, Ye J, Rahmadsyah, Alfiko Y, Jin J, Lieando J, Purnamasari M, Lim C, Suwanto A, Wong L, Chua N, Yue G. 2015. A consensus linkage map of oil palm and a major QTL for stem height. Scientific reports 5:8232. 2014年 Li R, Weldegergis BT, Li J, Jung C, Qu J, Sun Y, Qian H, Tee C, van Loon JJ, Dicke M, Chua NH, Liu SS, Ye J*. 2014. Virulence factors of geminivirus interact with MYC2 to subvert plant resistance and promote vector performance. The Plant cell 26:4991-5008. Ye J, Qu J, Mao HZ, Ma ZG, Rahman NE, Bai C, Chen W, Jiang SY, Ramachandran S, Chua NH. 2014. Engineering geminivirus resistance in Jatropha curcus. Biotechnology for biofuels 7:149. Ye J, Geng Y, Zhang B, Mao H, Qu J, Chua N. 2014. The Jatropha FT ortholog is a systemic signal regulating growth and flowering time. Biotechnology for biofuels 7:19. Ye J, Liu P, Zhu C, Qu J, Wang X, Sun Y, Sun F, Jiang Y, Yue G, Wang C. 2014. Identification of candidate genes JcARF19 and JcIAA9 associated with seed size traits in Jatropha. Functional & integrative genomics 14:757-766. Wang G, Sun Y, Xu R, Qu J, Tee C, Jiang X, Ye J*. 2014. DNA-A of a highly pathogenic Indian cassava mosaic virus isolated from Jatropha curcas causes symptoms in Nicotiana benthamiana. Virus genes 48:402-405. 2013年及以前 Wang C, Ye J, Tang W, Liu Z, Zhu C, Wang M, Wan J. 2013. Loop nucleotide polymorphism in a putative miRNA precursor associated with seed length in rice (Oryza sativa L.). International journal of biological sciences 9:578-586. Wang CM, Liu P, Sun F, Li L, Liu P, Ye J, Yue GH. 2012. Isolation and identification of miRNAs in Jatropha curcas. International journal of biological sciences 8:418-429. Qu J, Ye J#, Geng YF, Sun YW, Gao SQ, Zhang BP, Chen W, Chua NH. 2012. Dissecting functions of KATANIN and WRINKLED1 in cotton fiber development by virus-induced gene silencing. Plant physiology 160:738-748. Ye J*, Hong Y, Qu J, Wang C. 2012. Improvement of Jatropha oil by genetic transformation. Jatropha, Challenges for a New Energy Crop- Genetic Improvement and Biotechnology, vol. 2. Springer Science Publishers, New York. Qu J, Mao HZ, Chen W, Gao SQ, Bai YN, Sun YW, Geng YF, Ye J*. 2012. Development of marker-free transgenic Jatropha plants with increased levels of seed oleic acid. Biotechnology for biofuels 5:10. Qu J, Ye J, Fang R. 2012. Artificial MicroRNAs for Plant Virus Resistance, Antiviral Resistance in Plants: Methods and Protocols, Methods in Molecular Biology, vol. 894. Sun F, Liu P, Ye J, Lo LC, Cao S, Li L, Yue GH, Wang CM. 2012. An approach for jatropha improvement using pleiotropic QTLs regulating plant growth and seed yield. Biotechnology for biofuels 5:42. Gao S, Qu J, Chua NH, Ye J*. 2010. A new strain of Indian cassava mosaic virus causes a mosaic disease in the biodiesel crop Jatropha curcas. Archives of virology 155:607-612. Ye J, Qu J, Zhang JF, Geng YF, Fang RX. 2009. A critical domain of the Cucumber mosaic virus 2b protein for RNA silencing suppressor activity. FEBS letters 583:101-106. Ye J, Qu J, Bui HT, Chua NH. 2009. Rapid analysis of Jatropha curcas gene functions by virus-induced gene silencing. Plant biotechnology journal 7:964-976. Qu J, Ye J#, Fang R. 2007. Artificial microRNA-mediated virus resistance in plants. Journal of virology 81:6690-6699. Xu Y, Ye J#, Liu H, Cheng E, Yang Y, Wang W, Zhao M, Zhou D, Liu D, Fang R. 2008. DNA-templated CMV viral capsid proteins assemble into nanotubes. Chemical Communications 1:49-51. Ye J, Liu L, Xue Y, Qu J, Gao G, Fang R. 2007. Efficient depletion of multiple SARS-CoV mRNAs by a single small interfering RNA targeting the leader sequence. Progress in Biochemistry and Biophysics 34:1092-1100. 国际专利 Jian Ye, et al. Transcriptome and functional analysis reveals a single gene hybrid vigor for oil yield in oil palm. (US Provisional Patent Application No. 62/082,341) Jian Ye et al.. A method to enhance plant virus resistance. (United States patent, PCT/SG2014/00003) Jian Ye et al. Control of pests in plants. (U.S. Patent Application US 2012/02400288A1). Jian Ye et al. Virus induced gene silencing (VIGS) for functional analysis of genes in cotton. (United States Patent 20120096595). Jian Ye et al. Functional analysis of Jatropha curcas genes. (United States Patent 20110265233). Jian Ye et al. Genetic Transformation of Jatropha curcas. (United States Patent 20110247099 A1). Jian Ye et al. Increasing cotton fiber length by manipulating transcription factor. (United States Patent PCT/SG2012/000139). Jian Ye et al. Microsomal ω6 Oleate Desaturases. (U.S. patent application PCT/SG2011/000337).