个人简介 丁裕斌，教授，博士生导师。曾赴香港大学、美国匹兹堡大学和瑞典梅拉达伦大学学习，系郑裕彤博士奖学金和国家留学基金委公派博士后项目获得者，入选重庆市“高校中青年骨干教师”、留学人员回国创业创新支持计划（优秀）、重庆医科大学“优秀青年学者”等人才项目资助。“生殖与发育教育部国际合作联合实验室”学术骨干，英国研究理事会（RCUK）评审专家。在FASEB Journal，Hum Reprod，RVCT等杂志共发表SCI论文50余篇（第一或通讯作者19篇）。主持国家自然科学基金4项、国家重点研发计划（分题）1项（2018YFC1004401）、省部级（重庆市）4项、重庆市教委等自然科学、教改和横向合作等研究项目19项，资助总额330余万元。主研国家级、省部级项目20余项。指导本科生获国家级创新论坛/设计大赛一等奖和二等奖各1项。参编教材及专著2部。

科研项目 主持的科研项目 “双面”角色蛋白HMGB1通过核-浆双途径调控子宫内膜蜕膜化的机制及在反复流产中的作用研究，国家自然科学基金 NSFC，金额：55.0万元，No.81971391，起止日期：2020.01-2023.12 子宫容受性的建立与反复植入失败，科技部重点研发计划，金额：60.0万元，No.2018YFC1004401，骨干，起止日期：2019.01-2021.12 缺氧经DNA甲基化途径致滋养细胞合体化异常的分子机制及在子痫前期发生中的作用，国家自然科学基金 NSFC，金额：57.0万元，No.81671493，起止日期：2017.01-2020.12 缺氧/复氧致DNA甲基化协同调控的滋养细胞间质转化（EMT）障碍在子痫前期发生中的作用及机制研究，国家自然科学基金 NSFC，金额：70.0万元，No.81370731，起止日期：2014.01-2017.12 绒毛外滋养细胞（EVT）侵袭行为DNA甲基化调控机制研究，国家自然科学基金 NSFC，金额：17.0万元，No.30700898，起止日期：2008.01-2010.12 ACBP调控的脂肪酸β-氧化在蜕膜化过程中的作用和机制，重庆市科委基础科学与前沿技术研究（一般），金额：10.0万元，No.cstc2018jcyjAX0533，起止日期：2018.07-2021.06 缺氧诱导DNA甲基化异常对滋养细胞合体化的影响及在子痫前期发生中作用，重庆市科委基础科学与前沿技术研究（一般）， 金额：5.0万元，cstc2017jcyJAX0410起止日期：2017.07-2020.06 表观修饰调控的TPD52在滋养细胞侵袭中的功能研究，重庆市科委自然科学基金，金额：5.0万元，No.cstc2011jjA10085，起止日期：2011.09-2014.07 论文情况 Nelson W, Wang YX, Sakwari G, Ding YB*. Review of the effects of perinatal exposure to EDCs in animals and humans. Reviews of Environmental Contamination and Toxicology. Published on line on 26 May 2019. 2020; 251:131-184. DOI 10.1007/398_2019_30 (IF2018=7.0) Peng W, Tong C, Li L, Huang C, Ran Y, Chen X, Bai Y, Liu Y, Zhan J, Tan B, Luo X, Wang H, Wen L, Zhang C, Zhang H, Ding Y*, Qi H*, Baker N P. Trophoblast proliferation and invasion regulated by ACTN4 is impaired in early onset preeclampsia. FASEB J. 2019; 33(5): 6327-6338. doi: 10.1096/fj.201802058RR. (IF2018=5.595) Adu-Gyamfi EA, Wang YX*, Ding YB*. The interplay between thyroid hormones and the placenta: a comprehensive review. Biology of Reproduction. 09 September 2019. https://doi.org/10.1093/biolre/ioz182. (IF2018=2.96) du-Gyamfi EA, Ding YB*, Wang YX*. Regulation of placentation by the transforming growth factor beta superfamily. Biology of Reproduction, 30 September 2019 https://doi.org/10.1093/biolre/ioz186. (IF2018=2.96) Adu-Gyamfi EA, Lamptey J, Duan FM, Wang YX, Ding YB*. The transforming growth factor β superfamily as possible biomarkers of preeclampsia: a comprehensive review. Biomarkers in Medicine. Published online 27 September 2019. doi: 10.2217/bmm-2019-0208. (IF2018=2.268) Lan X, Fu LJ, Zhang J, Liu XQ, Zhang HJ, Zhang X, Ma MF, Chen XM, He JL, Li LB, Wang YX, Ding YB*. Bisphenol A (BPA) promotes trophoblast migration by increasing Integrin-β1 and MMP-9 via activating MAPK and PI3K signaling pathways and impairs mice placentation. Oncotarget. 2017, 8(31): 51507-51521. doi: 10.18632/oncotarget.17882. (IF2017=5.168) Zhang X, Fu LJ, Liu XQ, Hu ZY, Jiang Y, Gao RF, Feng Q, Lan X, Geng YQ, Chen XM, He JL, Wang YX, Ding YB*. The NM23 regulates decidualization through PI3K-Akt-mTOR signaling pathways in mice and humans. Hum Reprod. 2016 Oct;31(10):2339-2351. (IF2016=5.02) Feng Q, Hu ZY, Liu XQ, Zhang X, Lan X, Geng YQ, Chen XM, He JL, Wang YX, Ding YB*. The Stomatin-like protein 2 (Slp-2) is involved in endometrial stromal cell proliferation and differentiation during decidualization in mouse and human. Reproductive Biomedicine Online. 2017, 34(2):191–202. (IF2017=3.249) Lan X, Fu LJ, Hu ZY, Feng Q, Liu XQ, Zhang X, Chen XM, He JL, Wang YX, Ding YB*. Methylated Oligonucleotide (MON) induced E-cadherin promoter hypermethylation and associated decreased expression contribute to the Motility and Invasion of Human Trophoblast. Reprod Fertil Dev. 2017, 29(8):1509-1520. DOI: 10.1071/RD16031（(IF2017=2.105） Peng W, Chen Y, Luo X, Shan N, Lan X, Olson D, Zhang H, Ding YB * and Qi HB*. DNA methylation-associated repression of MEST/PEG1 gene expression contributes to the invasion of extravillous trophoblast cells. Placenta. 2016; 46:92-101. (IF2016= 2.759) Wu PH, Chen XM, Liu XQ, He JL, Feng Q, Lan X, Zhang X, Geng YQ, Wang YX, DingYB*. Activation of TRAIL receptor genes expression following DNA demethylation in placental choriocarcinoma and transformed cell lines. reproduction, fertility and development. Reprod Fertil Dev. 2016; 28(11) 1844-1853. (IF2016=2.656) Ding YB, He JL, Chen XM, Liu XQ#, Wang YX#. LongSAGE analysis of gene expression profile in mice endometrium during the window of implantation. Mol Biol Rep. 2013; 40(1):651-663. (SCI, IF2012=2.506) Gao RF, Liu XQ, Wang YX, Chen XM, Ding YB*, He JL #. The IGF2 expression in blood is not associated to its imprinting status in healthy pregnant Chinese women. Biological research. Biol Res 2012, 45(4): 351-356. (IF2012=1.129) Long CL, He JL, Liu XQ, Chen XM, Gao RF, Wang YX, Ding YB*. Dietary folate deficiency in pseudopregnant mice has no effect on homeobox a10 promoter methylation or expression. Reproductive Sciences. 2012; 19(12): 1268-1275 (IF2012=2.064) Ding YB, Long CL, Liu XQ, Chen XM, Guo LR, Xia YY, He JL*, Wang YX*. 5-Aza-2′-deoxycytidine leads to reduced embryo implantation and reduced expression of DNA methyltransferases and essential endometrial genes. PLoS ONE. 2012; 7(9): e45364. (IF2011=4.07) Ding YB, He JL, Liu XQ, Chen XM, Long CL, Wang YX*. Expression of DNA methyltransferases in the mouse uterus during early pregnancy and susceptibility to dietary folate deficiency. Reproduction. 2012; 144 (1): 91-100. (IF2012=3.555) Gao RF, He JL, Liu XQ, Ding YB*, Chen XM, Chen Q, Tan Y, Wang YX*. Evaluation of IGF2 Imprinting Status and the Levels of Folate Biomarkers in the Second Trimester Pregnant Chinese Women. J Reprod Med. 2011; 56 (5-6): 254-260. (IF2011=0.688)