陈航榕 教授

个人介绍

一、主要研究方向

1. 无机基纳米生物材料及其肿瘤诊断与协同治疗研究

2. 无机纳米催化材料设计合成、性能及应用研究

主要从事纳米介孔结构材料、多功能无机基肿瘤诊疗剂材料、新型环境及电化学催化材料等研究；作为项目或课题负责人先后主持承担了包括国家863、973、国家科技支撑计划、国家自然科学基金、中科院交叉合作团队、上海市纳米专项、技术标准专项等科研项目。培养毕业博士/硕士研究生20余人。担任福州大学、南京工业大学兼职教授；“无机材料学报”、“Scientific Reports ”等学术期刊编委；中国超声医学工程学会超声分子影像学专业委员会常务委员；中国生物医学工程学会生物医学光子学分会副秘书长等职。

二、奖励与荣誉

国家杰出青年科学基金获得者 （2012）

国家“万人计划”科技创新领军人才（2016）

科技部创新人才推进计划中青年科技创新领军人才（2014）

国家百千万人才工程 “有突出贡献中青年专家”（2013）

国务院政府特殊津贴专家 （2015）

国家自然科学二等奖（2011，排名第二）

上海市自然科学一等奖（2008，排名第二；2014，排名第五）

上海市标准化优秀技术成果二等奖（2011，排名第一）

中国科学院十大杰出妇女（2017）

上海市三八红旗手/标兵（2002/2010）

中国科学院朱李月华优秀研究生导师(2014)

上海市青年科技启明星（2005）/启明星跟踪计划（2010）

上海市优秀学术带头人计划（2014）

三、学术成果

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在Adv. Mater., Angew. Chem. Int. Ed., ACS Nano, Adv. Funct. Mater., Biomaterials等国际著名期刊上发表SCI学术论文200余篇；多篇入选ESI高被引用论文；他引总计7500余次，h因子47； 20余项国家发明专利获授权。

四、近五年代表性研究论文

1.Juan Mou, Tianquan Lin, Fuqiang Huang, Jianlin Shi andHangrong Chen*, A New Green Titania with Enhanced NIR Absorption for Mitochondria-Targeted Cancer Therapy,Theranostics, 2017; 7(6): 1531-1542.

2. Kun Zhang, Huixiong Xu, Xiaoqing Jia, Yu Chen, Ming Ma, Liping Sun, andHangrong Chen*, Ultrasound-Triggered Nitric Oxide Release Platform Based on Energy Transformation for Targeted Inhibition of Pancreatic Tumor,ACS Nano, 2016, 10,10816-10828.

3. Xiaojun Cai, Wei Gao, Linlin Zhang, Ming Ma, Tianzhi Liu, Wenxian Du, Yuanyi Zheng,Hangrong Chen*, and Jianlin Shi, Enabling Prussian Blue with Tunable Localized Surface Plasmon Resonances: Simultaneously Enhanced Dual-Mode Imaging and Tumor Photothermal Therapy,ACS Nano, 2016, 10,11115-11126.

4. Qianru Li, Gang Wan, Han Zhao, Linyu Pan, Ning Wang, Wanpeng Zhao, Xiaoxia Zhou, Xiangzhi Cui andHangrong Chen*，Nitrogen-doped Carbon Vesicles with Dual Iron-based Sites for Efficient Oxygen Reduction，ChemSusChem, 2017,10,499-505.

5. Yu, LD; Chen, Y*; Wu, MY; Cai, XJ; Yao, HL; Zhang, LL;Chen, HR*; Shi, JL*，"Manganese Extraction" Strategy Enables Tumor-Sensitive Biodegradability and Theranostics of Nanoparticles，J.Am.Chem.Soc., 2016, 138(31), 9881-9894.

6. Zhang, K; Li, P; He, YP; Bo, XW; Li, XL; Li, DD;Chen, HR*; Xu, HX*, Synergistic Retention Strategy of RGD Active Targeting and Radiofrequency-enhanced Permeability for Intensified RF&Chemotherapy Synergistic Tumor Treatment,Biomaterials, 2016,99,34-46.

7. Wan, G; Ma, M; Jia, A; Chen, LS; Chen, Y; Cui, XZ;Chen, HR*; Shi, JL, 3D hierarchical assembly of optimized heterogeneous carbon nanosheets for highly efficient electrocatalysis,J. Mater. Chem. A,2016, 4(30), 11625-11629.

8. Shige Wang, Xiang Li, Yu Chen, Xiaojun Cai, Heliang Yao, Wei Gao, Yuanyi Zheng, Xiao An*,Jianlin ShiandHangrong Chen*, A Facile One-Pot Synthesis of a Two-Dimensional MoS2/Bi2S3 Composite Theranostic Nanosystem for Multi-Modality Tumor Imaging and Therapy.Advanced Materials. 2015, 27(17),2775

9. J.Mou, C.Liu,P.Li, Y.Chen, H.Xu, C.Wei, L.Song*, J.Shi,H.Chen*, A facile synthesis of versatile Cu2-xS nanoprobe for enhanced MRI and infrared thermal/photoacoustic multimodal imaging,Biomaterials, 2015,57,12-21.

10. Cai XJ, Jia XQ, Gao W, Zhang K, Ma M, Wang SG, Zheng YY, Shi JL*,Chen HR*, A Versatile Nanotheranostic Agent for Efficient Dual-Mode Imaging Guided Synergistic Chemo-Thermal Tumor Therapy.Advanced Functional Materials, 2015, 25（17）2520-2529.

11. Cai XJ, Gao, W; Ma, M; Wu, MY; Zhang, LL; Zheng, YY;Chen, HR*; Shi, JL*, A Prussian blue-based Core-shell Hollow-structured Mesoporous Nanoparticle as a Smart Theranostic Agent with Ultrahigh pH-responsive Longitudinal Relaxivity,Adv.Mater.2015,27(41), 6382.

12. Shige Wang, Yu Chen,* Xiang Li, Wei Gao, Linlin Zhang, Jun Liu, Yuanyi Zheng ,Hangrong Chen,* and Jianlin Shi, Injectable 2D MoS2 -Integrated Drug Delivering Implantfor Highly Effi cient NIR-Triggered Synergistic TumorHyperthermia,Adv.Mater.2015,27,7117–7122.

13. Ma M, Xu HX,Chen HR*, Jia XQ, Zhang K, Wang Q, Shi JL* et al. A Drug-Perfluorocarbon Nanoemulsion with an Ultrathin Silica Coating for the Synergistic Effect of Chemotherapy and Ablation by High-Intensity Focused Ultrasound.Advanced Materials. 2014;26:7378-85.

14. Chen Y, Xu PF, Wu MY, Meng QS,Chen HR*, Shu Z, Shi JL* et al. Colloidal RBC-Shaped, Hydrophilic, and Hollow Mesoporous Carbon Nanocapsules for Highly Efficient Biomedical Engineering.Advanced Materials. 2014;26:4294-301.

15. Chen Y, Xu PF, Shu Z, Wu MY, Wang LZ, Zhang SJ,Chen HR*, Jianlin Shi* et al. Multifunctional Graphene Oxide-based Triple Stimuli-Responsive Nanotheranostics.Advanced Functional Materials. 2014;24:4386-96.

16. Chen Y, Jiang L, Wang RH, Lu M, Zhang QX, Zhou Y,Chen HR*, Zheng YI* et al. Injectable Smart Phase-Transformation Implants for Highly Efficient In Vivo Magnetic-Hyperthermia Regression of Tumors.Advanced Materials.2014;26:7468-73.

17. Yu Chen,Hangrong Chen* and Jianlin Shi*, Construction of Homogenous/Heterogeneous Hollow Mesoporous Silica Nanostructures by Silica-Etching Chemistry: Principles, Synthesis,and Applications,Accounts of Chemical Research, 2014,47,125-137.

18. Yu Chen,Hangrong Chen* and Jianlin Shi*, In Vivo Bio-Safety Evaluations and Diagnostic/Therapeutic Applications of Chemically Designed Mesoporous Silica Nanoparticles.,Advanced Materials,2013, 25, 3144–3176.

19. Yu Chen, PengfeiXu,Hangrong Chen*, Yongsheng Li, Wenbo Bu, Zhu Shu, Yaping Li, Jiamin Zhang, Lingxia Zhang, Limin Pan, Xiangzhi Cui, ZileHua, Jin Wang, Linlin Zhang and Jianlin Shi*, Colloidal HPMO Nanoparticles: Silica-Etching Chemistry Tailoring, Topological Transformation, and Nano-Biomedical Applications,Advanced Materials,2013, 25, 3100–3105.

20. Xia Wang,Hangrong Chen*, Yu Chen, Ming Ma, Kun Zhang, Faqi Li, Yuanyi Zheng, Deping Zeng, Qi Wang, Jianlin Shi*, Perfluorohexane-Encapsulated Mesoporous Silica Nanocapsules as a Highly Efficient HIFU Synergistic Agent,Advanced Materials, 2012, 24(6),785-791.

21. Ming Ma,Hangrong Chen*, Yu Chen, Xia Wang, Feng Chen, Xiangzhi Cui, Jianlin Shi*, Au Capped Magnetic Core/Mesoporous Silica Shell Nanoparticles For Combined Photothermo-/Chemo- Therapy And Multimodal Imaging,Biomaterials, 2012, 33, 989-998.

22. Yu Chen, Qi Yin,Shengjian Zhang,Hangrong Chen*, Yuanyi Zheng, Yang Sun, Jianlin Shi*, Manganese oxide-based multifunctionalized mesoporous silica nanoparticles for pH-responsive MRI, ultrasonography and circumvention of MDR in cancer cells，Biomaterials,2012,33,7126-7137.

23. Yu Chen, Yu Gao,Hangrong Chen*, Deping Zeng, Yaping Li, Yuanyi Zheng, Faqi Li, Xia Wang, Feng Chen, Qianjun He, Linlin Zhang and Jianlin Shi*, Engineering “Inorganic Nanoemulsion/Nanoliposome” by Fluoride-Silica Chemistry for Efficient Delivery/Co-delivery of Hydrophobic Agents,Advanced Functional Materials, 2012, 22,1586.

24. Yu Chen,Hangrong Chen*, Shengjian Zhang, Feng Chen, Shikuan Sun, Qianjun He, Ming Ma, Xia Wang, Huixia Wu, Lingxia Zhang and Jianlin Shi*, Structure-Property Relationships in Manganese oxide - Mesoporous Silica Nanoparticles Used for T1-Weighted MRI and Simultaneous Anticancer Drug Delivery,Biomaterials, 2012, 33(7),2388-2398.