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黄少胥(教授)

所属单位:中国科学院上海有机化学研究所

担任职务:副研究员

擅长领域:

联系方式:021-54925289 邮箱:登录后查看

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主要成就

{"awards": " ", "lunzhu": " .TRS_Editor P{font-family:宋体;font-size:10.5pt;}.TRS_Editor DIV{font-family:宋体;font-size:10.5pt;}.TRS_Editor TD{font-family:宋体;font-size:10.5pt;}.TRS_Editor TH{font-family:宋体;font-size:10.5pt;}.TRS_Editor SPAN{font-family:宋体;font-size:10.5pt;}.TRS_Editor FONT{font-family:宋体;font-size:10.5pt;}.TRS_Editor UL{font-family:宋体;font-size:10.5pt;}.TRS_Editor LI{font-family:宋体;font-size:10.5pt;}.TRS_Editor A{font-family:宋体;font-size:10.5pt;}1)Huang, Shao-Xu; Li, Hui-Yuan; Liu, Jun-Yan; Morisseau, Christophe; Hammock, Bruce D.; Long, Ya-Qiu*. Incorporation of Piperazino Functionality into 1,3-Disubstituted Urea as the Tertiary Pharmacophore Affording Potent Inhibitors of Soluble Epoxide Hydrolase with Improved Pharmacokinetic Properties. Journal of Medicinal Chemistry, 53(23), 8376-8386, 2010.2)Huang, Shao-Xu; Ding Kuiling*. Asymmetric bromoamination of chalcones with a privileged N,N'-dioxide/scandium(III) catalyst. Angewandte Chemie International Edition. 50(34), 7734-7736, 2011. (Highlight). 3)Huang, Shao-Xu; Cao, Bin; Morisseau, Christophe; Tin, Yi; Hammock, Bruce D.; Long, Ya-Qiu*. Structure-based optimization of the piperazino-containing 1,3-disubstituted ureas affording sub-nanomolar inhibitors of soluble epoxide hydrolase. MedChemComm, 3(3), 379-384, 2012. 4)黄少胥; 王勇; 龙亚秋*. 人类可溶性环氧化物水解酶抑制剂的研究进展. 《有机化学》, 05期, 877-888, 2012. 5)Long, Ya-Qiu*; Huang, Shao-Xu; Zawahir, Zahrah; Xu, Zhong-Liang; Li, Huiyuan; Sanchez, Tino W.; Zhi, Ying; De Houwer, Stephanie; Christ, Frauke; Debyser, Zeger; Neamati, Nouri*. Design of Cell-Permeable Stapled Peptides as HIV-1 Integrase Inhibitors. Journal of Medicinal Chemistry, 56(13), 5601–5612, 2013. "}