主要成就
{"yanjiu_chengguo":"截止目前，在ChemicalCommunication，ActaBiomaterialia，Biomacromolecules，Nanoscale等国际著名刊物上发表SCI论文60余篇，研究论文累计被他人正面引用达1000余次，目前个人H影响因子20，申请国家发明专利10余项，授权1项。成果曾获2014年度甘肃省高校科技进步奖一等奖（本人排名第三），担任重庆功能材料学会理事。","xiangmu":"1、GSH/pH响应型星形聚合物前药的设计、构建及靶向抗肿瘤研究，国家自然科学基金（51703187），2018.01-2020.12，22万，项目负责人2、激活型单分子胶束药物载体的设计及抗肿瘤性能研究，重庆市基础研究与前沿探索项目（cstc2018jcyjAX0104），2018.07-2021.06，10万，项目负责人3.星形聚合物荧光探针的设计、合成及在肿瘤早期诊断中的应用，四川省应用基础研究计划（面上项目，2018JY0392），2018.07-2020.06，10万，项目负责人4、pH敏感型星形单分子聚合物的构建及其在肿瘤诊断与治疗中的应用，重庆市基础与前沿研究计划项目（cstc2016jcyjA0078），2016.07-2019.06，5万，项目负责人5、智能型小分子药物传递系统的设计、合成及其在癌症治疗中的应用研究，中央高校基本科研业务费一般项目（XDJK2016C004），2016.01-2017.12，5万，项目负责人6、西南大学人才引进基金（SWU115058），2016.01-2018.12，20万，项目负责人","lunzhu":"1.XiaoqianMa,XiaoxiaoShi,ShuangBai,JianjianZhang,MeiliHou,TianZhang,Bao-shengLi,PengXue,YuejunKang*,ZhigangXu*,Water-solubleFluorescentUnimolecularMicelles:Ultra-smallsize,tunablefluorescenceemissionfromvisibletoNIRregionandenhancedbiocompatibilityforinvitroandinvivobioimaging,Chem.Commun.,2018,54,6252-6255.(IF2017=6.290,Frontcover)2.MeiliHou,Yong-EGao,XiaoxiaoShi,ShuangBai,XiaoqianMa,BaoshengLi,BoXiao,PengXue,YuejunKang*,ZhigangXu*,Methotrexate-basedamphiphilicprodrugnanoaggregatesforco-administrationofmultipletherapeuticsandsynergisticcancertherapy.ActaBiomaterialia,2018,77,228-239(IF2017=6.383)3.ShuangBai,XiaoliZhang,XiaoqianMa,JiuncunChen,QiubingChen,XiaoxiaoShi,MeiliHou,PengXue,YuejunKang*,ZhigangXu*,Acid-activesupramolecularanticancernanoparticlesbasedoncyclodextrinpolyrotaxanesdamagingbothmitochondriaandnucleioftumorcells.BiomaterialsScience,2018,6,3126-3138.(IF2017=5.831,Frontcover).4.XiaoxiaoShi,ShuangBai,CangjieYang,XiaoqianMa,MeiliHou,JiucunChen,PengXue,ChangMingLi,YuejunKang*,ZhigangXu*,Improvingthecarrierstabilityanddrugloadingofunimolecularmicelle-basednanotherapeuticsforacid-activateddrugdeliveryandenhancedantitumortherapy.JournalofMaterialsChemistryB,2018,6,5549-5561.(IF2017=4.776,Backcover)5.ShuangBai,MeiliHou,XiaoxiaoShi,JiuncunChen,XiaoqianMa,Yong-EGao,YajunWang,PengXue,YuejunKang*,ZhigangXu*,Reduction-activepolymericprodrugmicellesbasedonα-cyclodextrinpolyrotaxanesfortriggereddrugreleaseandenhancedcancertherapy,CarbohydratePolymers,2018,193,153-162.(IF2017=5.158)6.ShuangBai,Yong-EGao,XiaoqianMa,XiaoxiaoShi,MeiliHou,PengXue*,YuejunKang*,ZhigangXu*,Reductionstimuli-responsiveunimolecularpolymericprodrugbasedonamphiphilicdextran-frameworkforantitumordrugdelivery,CarbohydratePolymers,CarbohydratePolymers,2018,182,235-244.(IF2017=5.158)7.XiaoxiaoShi,XiaoqianMa,MeiliHou,Yong-EGao,ShuangBai,BoXiao,PengXue,YuejunKang,ZhigangXu*,ChangMingLi,pH-responsiveunimolecularmicellesbasedonamphiphilicstar-likecopolymerswithhighdrugloadingforeffectivedrugdeliveryandcellularimaging,JournalofMaterialsChemistryB,2017,5,6847-6859.(IF2017=4.776)8.XiaoxiaoShi,MeiliHou,ShuangBai,XiaoqianMa,Yong-EGao,BoXiao,PengXue,YuejunKang*,ZhigangXu*,ChangMingLi,Acid-ActivatableTheranosticUnimolecularMicellesComposedofAmphiphilicStar-likePolymericProdrugwithHighDrugLoadingforEnhancedCancerTherapy,MolecularPharmaceutics,2017,14,4032-4041.(IF2017=4.556)9.MeiliHou,PengXue,Yong-EGao,XiaoqianMa,ShuangBai,YuejunKang*,ZhigangXu*,Gemcitabine–camptothecinconjugates:ahybridprodrugforcontrolleddrugreleaseandsynergistictherapeutics,BiomaterialsScience,2017,5,1889-1897.(IF2017=5.831).10.ZhigangXu,ShiyingLiu,HuiLiu,CangjieYang,YuejunKangandMingfengWang*,Unimolecularmicellesofamphiphiliccyclodextrin-corestar-likeblockcopolymersforanticancerdrugdelivery,ChemicalCommunication,2015,51,15768-15771.(IF2017=6.290)","zhuanli":"。。。"}
